Crypto portfolio companies represent the most innovative blockchain startups, backed by leading venture capital funds and accelerators. These projects are shaping the future of DeFi, NFTs, infrastructure, and Web3 ecosystems, driving adoption and pushing the boundaries of what’s possible.
Explore the top portfolio companies of 2025 funded by renowned VCs like a16z, Paradigm, and Pantera Capital, and discover the projects leading blockchain innovation.
10,000 TPS
1 Second
EigenLayer, EigenDA
Empower Open Innovation
AI Assets
Decentralized AI Development
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Read this articleMonad Labs is a next-generation blockchain infrastructure company that is pioneering high-performance Layer 1 solutions for decentralized applications. The project focuses on delivering unmatched speed and efficiency with full compatibility for Ethereum Virtual Machine (EVM) applications. By combining parallel execution with pipelined consensus, Monad is able to achieve 10,000 transactions per second and single-slot finality—bringing scalability without sacrificing security or decentralization.
Monad's architecture makes it easy for developers to port over existing Ethereum-based dApps without rewriting smart contracts. This allows for seamless transitions and fast deployment of DeFi protocols, NFT marketplaces, and other Web3 applications, while offering end-users significantly lower gas fees and faster confirmation times.
With its advanced execution engine and innovative consensus mechanism, Monad Labs is positioning itself as a competitive alternative to other Layer 1s while preserving Ethereum compatibility. The team consists of seasoned engineers and crypto-native builders committed to solving the blockchain trilemma of scalability, security, and decentralization.
As adoption grows, Monad could become a core platform in the broader Web3 stack—delivering the speed and performance needed for the next wave of decentralized apps and services.
10,000 TPS
1 Second
Building a high-performance, EVM-compatible Layer 1 blockchain with 10,000 TPS and single-slot finality.
Eigen Labs is the creator behind EigenLayer and EigenDA, two powerful protocols designed to enhance the scalability and security of Ethereum and other decentralized networks. Through the concept of restaking, EigenLayer enables users to reuse their ETH staking collateral to secure additional protocols, driving capital efficiency and composability in the Ethereum ecosystem.
The company’s second innovation, EigenDA (Data Availability), improves on-chain data availability by allowing rollups and Layer 2 protocols to publish their data on a decentralized network with strong guarantees. This increases throughput and scalability while minimizing trust assumptions.
Eigen Labs is focused on promoting open innovation through modular blockchain components. Its technology stack provides developers with the tools needed to build decentralized services more efficiently while maintaining Ethereum’s security guarantees. The team collaborates closely with the Ethereum research community and has attracted strong interest from the broader DeFi and rollup ecosystem.
By advancing modularity and enabling new economic models in crypto infrastructure, Eigen Labs is shaping the future of Ethereum scalability and empowering developers to build more powerful decentralized applications.
EigenLayer, EigenDA
Empower Open Innovation
Empowering open innovation through protocols like EigenLayer and EigenDA, enhancing Ethereum's scalability and security.
Sahara AI is building a decentralized infrastructure for artificial intelligence development, data sharing, and monetization. The platform empowers users to contribute and profit from AI models and datasets through tokenized ownership and decentralized governance. By operating on-chain, Sahara provides transparency and immutability—enabling fair and open collaboration for AI innovators.
One of Sahara AI’s most innovative concepts is that of “AI Assets,” which formalize the ownership of datasets and algorithms. These assets can be licensed, monetized, or improved collaboratively, creating a dynamic ecosystem where developers, researchers, and contributors are fairly rewarded for their efforts.
Sahara is also committed to privacy and ethical AI use. It leverages blockchain to enforce user consent and data sovereignty, ensuring that contributors retain control over how their data and models are used. This is particularly important in industries like healthcare, finance, and social media, where data privacy is paramount.
With a strong emphasis on decentralization, interoperability, and transparent incentive mechanisms, Sahara AI is at the frontier of the decentralized AI revolution—bridging the gap between Web3 infrastructure and artificial intelligence innovation.
AI Assets
Decentralized AI Development
Creating a decentralized AI blockchain platform for collaborative development and monetization of AI assets.
Portfolio companies are blockchain startups that have received funding from venture capital firms, incubators, or accelerators. These companies often represent the cutting edge of innovation in crypto and Web3.
| Project | Sector | Backers | Visit |
|---|---|---|---|
| Uniswap | DeFi (DEX) | a16z, Paradigm | Visit |
| Polygon | Layer 2 scaling | Sequoia, Binance Labs | Visit |
| dYdX | DeFi derivatives | Paradigm, a16z | Visit |
| The Sandbox | Gaming, metaverse | Animoca Brands, SoftBank | Visit |
| Axie Infinity | Gaming, NFTs | Delphi Digital, a16z | Visit |
| Lido Finance | Liquid staking | Paradigm, Dragonfly Capital | Visit |
| Helium | DePIN (IoT) | Multicoin Capital, a16z | Visit |
| LayerZero | Cross-chain infrastructure | Sequoia, a16z | Visit |
| Avalanche | Layer 1 blockchain | Polychain Capital, Three Arrows | Visit |
| Optimism | Layer 2 scaling | Paradigm, a16z | Visit |
These portfolio companies are leaders in blockchain innovation and adoption.
These sectors are driving blockchain’s evolution in 2025.
Portfolio companies are the front-runners in blockchain innovation.
Crypto portfolio companies are pioneers shaping the next generation of Web3. Backed by top VCs, these startups lead the charge in driving real-world adoption and technological breakthroughs.
Discover leading crypto portfolio companies and connect with the innovators of blockchain in 2025. 🚀🌐₿
A seasoned innovator in the gaming and tech world, with nearly two decades of hands-on experience bridging the gap between emerging technologies and interactive entertainment. Since 2006, he has been at the forefront of industry evolution - from early online gaming ecosystems to today's cutting-edge game development tools, streaming platforms, and Web3 integrations.
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